Most hypotheses suggest that earlier forms of life had partial genetic codes and used fewer than 20 amino acids. To test ...

Just as the human body relies on organs such as the heart or liver for essential functions, cells depend on their own tiny ...

Advanced non-viral gene delivery systems are expanding the range of indications and therapy modalities possible for the new generation of genetic medicines.

Lipid nanoparticles address key drug delivery challenges, including immune evasion, toxicity, and regulatory approval.

Understanding the biological, medical and ecological pathways of complex transformations will be greatly aided by the chemist's molecular approach. The 2 nd European Conference on Chemistry for Life ...

Ligands may be small molecules, but their impact on biology is massive—from stabilizing protein structures to driving drug ...

This manuscript has convincing data that provides a high-resolution structure of the Egl-RNA complex. The findings are important to understand the formation, stability, and interactions of this ...

An engineered E. coli strain survived after one amino acid was designed out of many of its ribosomal proteins—an early test ...

AI-guided redesign of protein alphabet in bacteria could unlock new ways to build synthetic organisms.

Computational assessment identifies probe binding errors in a widely used commercial platform for spatial transcriptomics.

Proteins are life’s molecular machines, built from amino acids whose sequences and side chains dictate their structure and function. From essential dietary amino acids to complex folding patterns, ...